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Human GPR77 (1-38) Protein, hFc Tag

Recombinant Human GPR77(1-38) with C-terminal human Fc tag


Cat.#:  11464

   Size:   100 μg

In Stock

          Product Description          
Cat.#:     11464
Product Name:   Human GPR77 (1-38) Protein
Size :    10 µg, 50 µg and 100 µg
Synonyms:   C5L2;GPF77;GPR77
Target:    GPR77
Description:    Recombinant Human GPR77(1-38) with C-terminal human Fc tag
Background:     This gene encodes a G-protein coupled receptor 1 family member involved in the complement system of the innate immune response. Unlike classical G-protein coupled receptors, the encoded protein does not associate with intracellular G-proteins. It may instead modulate signal transduction through the beta-arrestin pathway, and may alternatively act as a decoy receptor. This gene may be involved in coronary artery disease and in the pathogenesis of sepsis. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Nov 2012]
Species/Host:    HEK293
Molecular Weight:    The protein has a predicted molecular mass of 30.2 kDa after removal of the signal peptide. The apparent molecular mass of GPR77(1-38)-hFc is approximately 35-55 kDa due to glycosylation.
Molecular Characterization:    GPR77(Met1-Pro38) hFc(Glu99-Ala330)
Purity:    The purity of the protein is greater than 95% as determined by SDS-PAGE and Coomassie blue staining.
Formulation & Reconstitution:    Lyophilized from nanodisc solubilization buffer (20 mM Tris-HCl, 150 mM NaCl, pH 8.0). Normally 5% – 8% trehalose is added as protectants before lyophilization.
Storage & Shipping:    Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.

Figure 1. Human GPR77(1-38) Protein, hFc Tag on SDS-PAGE under reducing condition.