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Human ITGA2 Protein, His Tag

Recombinant human ITGA2 Protein with C-terminal 6XHis tag


Cat.#:  11498

   Size:   100 μg

In Stock

          Product Description          
Cat.#:     11498
Product Name:   Human ITGA2 Protein
Size :    10 µg, 50 µg and 100 µg
Synonyms:   Integrin alpha-2;Collagen receptor;GPIa;CD49b
Target:    ITGA2
UNIPROT ID:    P17301
Description:    Recombinant human ITGA2 Protein with C-terminal 6xHis tag
Background:     This gene encodes the alpha subunit of a transmembrane receptor for collagens and related proteins. The encoded protein forms a heterodimer with a beta subunit and mediates the adhesion of platelets and other cell types to the extracellular matrix. Loss of the encoded protein is associated with bleeding disorder platelet-type 9. Antibodies against this protein are found in several immune disorders, including neonatal alloimmune thrombocytopenia. This gene is located adjacent to a related alpha subunit gene. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2012]
Species/Host:    HEK293
Molecular Weight:    The protein has a predicted molecular mass of 121.8 kDa after removal of the signal peptide. The apparent molecular mass of ITGA2-His is approximately 130-250 kDa due to glycosylation.
Molecular Characterization:    ITGA2(Thr30-Thr1132) 6×His tag
Purity:    The purity of the protein is greater than 85% as determined by SDS-PAGE and Coomassie blue staining.
Formulation & Reconstitution:    Lyophilized from nanodisc solubilization buffer (20 mM Tris-HCl, 150 mM NaCl, pH 8.0). Normally 5% – 8% trehalose is added as protectants before lyophilization.
Storage & Shipping:    Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.

Figure 1. Human ITGA2, His Tag on SDS-PAGE under reducing condition.