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Human LAG3 Protein, hFc Tag

Recombinant human LAG3 Protein with C-terminal Human Fc tag


Cat.#:  11316

   Size:   100 μg

In Stock

          Product Description          
Cat.#:     11316
Product Name:   Human LAG3 Protein
Size :    10 µg, 50 µg and 100 µg
Synonyms:   LAG-3;CD223
Target:    LAG3
UNIPROT ID:    P18627
Description:    Recombinant human LAG3 Protein with C-terminal Human Fc tag
Background:     Lymphocyte-activation protein 3 belongs to Ig superfamily and contains 4 extracellular Ig-like domains. The LAG3 gene contains 8 exons. The sequence data, exon/intron organization, and chromosomal localization all indicate a close relationship of LAG3 to CD4. [provided by RefSeq, Jul 2008]
Species/Host:    HEK293
Molecular Weight:    The protein has a predicted molecular mass of 72.3 kDa after removal of the signal peptide.The apparent molecular mass of LAG3-hFc is approximately 100-130 kDa due to glycosylation.
Molecular Characterization:    LAG3(Leu23-Leu245) hFc(Glu99-Ala330)
Purity:    The purity of the protein is greater than 95% as determined by SDS-PAGE and Coomassie blue staining.
Formulation & Reconstitution:    Lyophilized from nanodisc solubilization buffer (20 mM Tris-HCl, 150 mM NaCl, pH 8.0). Normally 5% – 8% trehalose is added as protectants before lyophilization.
Storage & Shipping:    Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.

Figure 1. Human LAG3 Protein, hFc Tag on SDS-PAGE under reducing condition.