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Human LAIR1 Protein, hFc Tag

Recombinant Human LAIR1 Protein with C-terminal human Fc tag
5/5

$389.00

Cat.#:  11909

   Size:   100 μg

In Stock

            Product Description          
Cat.#:     11909
Product Name:   Human LAIR1 Protein
Size :    10 µg, 50 µg and 100 µg
Synonyms:   CD305;LAIR-1
Target:    LAIR1
UNIPROT ID:    Q6GTX8
Description:    Recombinant Human LAIR1 Protein with C-terminal human Fc tag
Background:     The protein encoded by this gene is an inhibitory receptor found on peripheral mononuclear cells, including natural killer cells, T cells, and B cells. Inhibitory receptors regulate the immune response to prevent lysis of cells recognized as self. The gene is a member of both the immunoglobulin superfamily and the leukocyte-associated inhibitory receptor family. The gene maps to a region of 19q13.4 called the leukocyte receptor cluster, which contains at least 29 genes encoding leukocyte-expressed receptors of the immunoglobulin superfamily. The encoded protein has been identified as an anchor for tyrosine phosphatase SHP-1, and may induce cell death in myeloid leukemias. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2014]
Species/Host:    HEK293
Molecular Weight:    The protein has a predicted molecular mass of 41.6 kDa after removal of the signal peptide. The apparent molecular mass of LAIR1-hFc is approximately 35-70 kDa due to glycosylation.
Molecular Characterization:    LAIR1(Gln22-His163) hFc(Glu99-Ala330)
Purity:    The purity of the protein is greater than 95% as determined by SDS-PAGE and Coomassie blue staining.
Formulation & Reconstitution:    Lyophilized from nanodisc solubilization buffer (20 mM Tris-HCl, 150 mM NaCl, pH 8.0). Normally 5% – 8% trehalose is added as protectants before lyophilization.
Storage & Shipping:    Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.

Figure 1.Human LAIR1 Protein, hFc Tag on SDS-PAGE under reducing condition.
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