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Human LOX-1 Protein, hFc Tag

Recombinant Human? LOX-1 Protein with N-terminal human Fc tag


Cat.#:  11968

   Size:   100 μg

In Stock

          Product Description          
Cat.#:     11968
Product Name:   Human LOX-1 Protein
Size :    10 µg, 50 µg and 100 µg
Target:    LOX-1
UNIPROT ID:    P78380
Description:    Recombinant Human LOX-1 Protein with N-terminal human Fc tag
Background:     This gene encodes a low density lipoprotein receptor that belongs to the C-type lectin superfamily. This gene is regulated through the cyclic AMP signaling pathway. The encoded protein binds, internalizes and degrades oxidized low-density lipoprotein. This protein may be involved in the regulation of Fas-induced apoptosis. This protein may play a role as a scavenger receptor. Mutations of this gene have been associated with atherosclerosis, risk of myocardial infarction, and may modify the risk of Alzheimer's disease. Alternate splicing results in multiple transcript variants.[provided by RefSeq, Feb 2010]
Species/Host:    HEK293
Molecular Weight:    The protein has a predicted molecular mass of 50.9 kDa after removal of the signal peptide. The apparent molecular mass of hFc-LOX-1 is approximately 55-70 kDa due to glycosylation.
Molecular Characterization:    hFc(Glu99-Ala330) LOX-1(Met58-Gln273)
Purity:    The purity of the protein is greater than 95% as determined by SDS-PAGE and Coomassie blue staining.
Formulation & Reconstitution:    Lyophilized from nanodisc solubilization buffer (20 mM Tris-HCl, 150 mM NaCl, pH 8.0). Normally 5% – 8% trehalose is added as protectants before lyophilization.
Storage & Shipping:    Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.

Figure 1.Human LOX-1 Protein, hFc Tag on SDS-PAGE under reducing condition.