Subtotal:
$239.00
$555.00
| Cat.#: 11368 | ||
| Product Name: Human M-CSF Protein | ||
| Size : 10 µg, 50 µg and 100 µg | ||
| Synonyms: CSF-1;MCSF | ||
| Target: M-CSF | ||
| UNIPROT ID: P09603 | ||
| Description: Recombinant Human M-CSF with C-terminal mouse Fc tag | ||
| Background: The protein encoded by this gene is a cytokine that controls the production, differentiation, and function of macrophages. The active form of the protein is found extracellularly as a disulfide-linked homodimer, and is thought to be produced by proteolytic cleavage of membrane-bound precursors. The encoded protein may be involved in development of the placenta. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Sep 2011] | ||
| Species/Host: HEK293 | ||
| Molecular Weight: The protein has a predicted molecular mass of 51.2 kDa after removal of the signal peptide.The apparent molecular mass of M-CSF-mFc is approximately 55-75 kDa due to glycosylation. | ||
| Molecular Characterization: M-CSF(Glu33-Arg255) mFc(Pro99-Lys330) | ||
| Purity: The purity of the protein is greater than 95% as determined by SDS-PAGE and Coomassie blue staining. | ||
| Formulation & Reconstitution: Lyophilized from nanodisc solubilization buffer (20 mM Tris-HCl, 150 mM NaCl, pH 8.0). Normally 5% – 8% trehalose is added as protectants before lyophilization. | ||
| Storage & Shipping: Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature. | ||
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