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Human MST1R Protein, hFc Tag

Recombinant Human MST1R Protein with C-terminal Human Fc tag


Cat.#:  11602

   Size:   100 μg

In Stock

          Product Description          
Cat.#:     11602
Product Name:   Human MST1R Protein
Size :    10 µg, 50 µg and 100 µg
Synonyms:   CD136;CDw136;NPCA3;PTK8;RON
Target:    MST1R
UNIPROT ID:    Q04912
Description:    Recombinant Human MST1R Protein with C-terminal Human Fc tag
Background:     This gene encodes a cell surface receptor for macrophage-stimulating protein (MSP) with tyrosine kinase activity. The mature form of this protein is a heterodimer of disulfide-linked alpha and beta subunits, generated by proteolytic cleavage of a single-chain precursor. The beta subunit undergoes tyrosine phosphorylation upon stimulation by MSP. This protein is expressed on the ciliated epithelia of the mucociliary transport apparatus of the lung, and together with MSP, thought to be involved in host defense. Alternative splicing generates multiple transcript variants encoding different isoforms that may undergo similar proteolytic processing. [provided by RefSeq, Jan 2016]
Species/Host:    HEK293
Molecular Weight:    The protein has a predicted molecular mass of 125.9 kDa after removal of the signal peptide. The apparent molecular mass of MST1R-hFc is approximately 130-250 kDa due to glycosylation.
Molecular Characterization:    MST1R(Glu25-Thr957) hFc(Glu99-Ala330)
Purity:    The purity of the protein is greater than 95% as determined by SDS-PAGE and Coomassie blue staining.
Formulation & Reconstitution:    Lyophilized from nanodisc solubilization buffer (20 mM Tris-HCl, 150 mM NaCl, pH 8.0). Normally 5% – 8% trehalose is added as protectants before lyophilization.
Storage & Shipping:    Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.

Figure 1. Human MST1R Protein, hFc Tag on SDS-PAGE under reducing condition.

Figure 2. ELISA plate pre-coated by 2 µg/ml (100 µl/well) Human MST1R Protein, hFc Tag (11602) can bind Anti-MST1R Neutralizing antibody 28116 in a linear range of 0.73-46.88 ng/mL.