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Human NKG2A Protein, hFc Tag

Recombinant Human NKG2A Protein with N-terminal human Fc tag
5/5

$389.00

Cat.#:  11629

   Size:   100 μg

In Stock

          Product Description          
Cat.#:     11629
Product Name:   Human NKG2A Protein
Size :    10 µg, 50 µg and 100 µg
Synonyms:   CD159A;NKG2;NKG2A
Target:    NKG2A
UNIPROT ID:    P26715
Description:    Recombinant Human NKG2A Protein with N-terminal human Fc tag
Background:     Natural killer (NK) cells are lymphocytes that can mediate lysis of certain tumor cells and virus-infected cells without previous activation. They can also regulate specific humoral and cell-mediated immunity. The protein encoded by this gene belongs to the killer cell lectin-like receptor family, also called NKG2 family, which is a group of transmembrane proteins preferentially expressed in NK cells. This family of proteins is characterized by the type II membrane orientation and the presence of a C-type lectin domain. This protein forms a complex with another family member, KLRD1/CD94, and has been implicated in the recognition of the MHC class I HLA-E molecules in NK cells. The genes of NKG2 family members form a killer cell lectin-like receptor gene cluster on chromosome 12. Multiple alternatively spliced transcript variants encoding distinct isoforms have been observed. [provided by RefSeq, Jan 2015]
Species/Host:    HEK293
Molecular Weight:    The protein has a predicted molecular mass of 42.2 kDa after removal of the signal peptide.The apparent molecular mass of hFc-NKG2A is approximately 35-55 kDa due to glycosylation.
Molecular Characterization:    hFc(Glu99-Ala330) NKG2A(Pro94-Leu233)
Purity:    The purity of the protein is greater than 95% as determined by SDS-PAGE and Coomassie blue staining.
Formulation & Reconstitution:    Lyophilized from nanodisc solubilization buffer (20 mM Tris-HCl, 150 mM NaCl, pH 8.0). Normally 5% – 8% trehalose is added as protectants before lyophilization.
Storage & Shipping:    Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.

Figure 1. Human NKG2A Protein, hFc Tag on SDS-PAGE under reducing condition.
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