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Human NTB-A Protein, mFc-His Tag

Recombinant human NTB-A protein with C-terminal mouse Fc and 6XHis tag


Cat.#:  11183

   Size:   100 μg

In Stock

          Product Description          
Cat.#:     11183
Product Name:   Human NTB-A Protein
Size :    10 µg, 50 µg and 100 µg
Synonyms:   NTB-A;LAMF6;y108;K-T-B-antigen;D352;ALI
Target:    NTB-A
Description:    Recombinant human NTB-A protein with C-terminal mouse Fc and 6xHis tag
Background:     The protein encoded by this gene is a type I transmembrane protein, belonging to the CD2 subfamily of the immunoglobulin superfamily. This encoded protein is expressed on Natural killer (NK), T, and B lymphocytes. It undergoes tyrosine phosphorylation and associates with the Src homology 2 domain-containing protein (SH2D1A) as well as with SH2 domain-containing phosphatases (SHPs). It functions as a coreceptor in the process of NK cell activation. It can also mediate inhibitory signals in NK cells from X-linked lymphoproliferative patients. Alternative splicing results in multiple transcript variants encoding distinct isoforms.
Species/Host:    HEK293
Molecular Weight:    The protein has a predicted molecular mass of 50.1 kDa after removal of the signal peptide.
Molecular Characterization:    NTB-A(Gln22-Met226) mFc(Pro99-Lys330) 6×His tag
Purity:    The purity of the protein is greater than 95% as determined by SDS-PAGE and Coomassie blue staining.
Formulation & Reconstitution:    Lyophilized from nanodisc solubilization buffer (20 mM Tris-HCl, 150 mM NaCl, pH 8.0). Normally 5% – 8% trehalose is added as protectants before lyophilization.
Storage & Shipping:    Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.

Figure 1. Human NTB-A Protein, mFc-His Tag on SDS-PAGE under reducing condition.