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Human NTS Protein, hFc Tag

Recombinant human NTS protein with C-terminal human Fc tag
5/5

$550.00

Cat.#:  11580

   Size:   100 μg

In Stock

            Product Description          
Cat.#:     11580
Product Name:   Human NTS Protein
Size :    10 µg, 50 µg and 100 µg
Synonyms:   Neurotensin;neuromedin N
Target:    NTS
UNIPROT ID:    P30990
Description:    Recombinant human NTS protein with C-terminal human Fc tag
Background:     This gene encodes a common precursor for two peptides, neuromedin N and neurotensin. Neurotensin is a secreted tridecapeptide, which is widely distributed throughout the central nervous system, and may function as a neurotransmitter or a neuromodulator. It may be involved in dopamine-associated pathophysiological events, in the maintenance of gut structure and function, and in the regulation of fat metabolism. Neurotensin also exhibits antimicrobial activity against bacteria and fungi. Tissue-specific processing may lead to the formation in some tissues of larger forms of neuromedin N and neurotensin. The large forms may represent more stable peptides that are also biologically active. [provided by RefSeq, Oct 2014]
Species/Host:    HEK293
Molecular Weight:    The protein has a predicted molecular mass of 40.4 kDa after removal of the signal peptide. The apparent molecular mass of NTS-hFc is approximately 35-55 kDa due to glycosylation.
Molecular Characterization:    NTS(Ser24-Leu148) hFc(Glu99-Ala330)
Purity:    The purity of the protein is greater than 95% as determined by SDS-PAGE and Coomassie blue staining.
Formulation & Reconstitution:    Lyophilized from nanodisc solubilization buffer (20 mM Tris-HCl, 150 mM NaCl, pH 8.0). Normally 5% – 8% trehalose is added as protectants before lyophilization.
Storage & Shipping:    Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.

Figure 1. Human NTS Protein, hFc Tag on SDS-PAGE under reducing condition.
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