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Human PAI1 Protein, His Tag

Recombinant Human PAI1 Protein with C-terminal 6XHis tag
5/5

$389.00

Cat.#:  11961

   Size:   100 μg

In Stock

          Product Description          
Cat.#:     11961
Product Name:   Human PAI1 Protein
Size :    10 µg, 50 µg and 100 µg
Synonyms:   PAI;PAI-1;SERPINE1;PLANH1
Target:    PAI1
UNIPROT ID:    P05121
Description:    Recombinant Human PAI1 Protein with C-terminal 6XHis tag
Background:     This gene encodes a member of the serine proteinase inhibitor (serpin) superfamily. This member is the principal inhibitor of tissue plasminogen activator (tPA) and urokinase (uPA), and hence is an inhibitor of fibrinolysis. The protein also functions as a component of innate antiviral immunity. Defects in this gene are the cause of plasminogen activator inhibitor-1 deficiency (PAI-1 deficiency), and high concentrations of the gene product are associated with thrombophilia. [provided by RefSeq, Aug 2020]
Species/Host:    HEK293
Molecular Weight:    The protein has a predicted molecular mass of 43.6 kDa after removal of the signal peptide. The apparent molecular mass of PAI1-His is approximately 35-55 kDa due to glycosylation.
Molecular Characterization:    PAI1(Val24-Pro402) 6×His tag
Purity:    The purity of the protein is greater than 85% as determined by SDS-PAGE and Coomassie blue staining.
Formulation & Reconstitution:    Lyophilized from nanodisc solubilization buffer (20 mM Tris-HCl, 150 mM NaCl, pH 8.0). Normally 5% – 8% trehalose is added as protectants before lyophilization.
Storage & Shipping:    Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.

Figure 1.Human PAI1 Protein, His Tag on SDS-PAGE under reducing condition.
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