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Human PRTN3 Protein, His Tag

Recombinant Human PRTN3 Protein with C-terminal 6XHis tag
5/5

$689.00

Cat.#:  11817

   Size:   100 μg

In Stock

            Product Description          
Cat.#:     11817
Product Name:   Human PRTN3 Protein
Size :    10 µg, 50 µg and 100 µg
Synonyms:   ACPA;AGP7;C-ANCA;CANCA;MBN;MBT;NP-4;NP4;P29;PR-3;PR3
Target:    PRTN3
UNIPROT ID:    P24158
Description:    Recombinant Human PRTN3 Protein with C-terminal 6xHis tag
Background:     Serine protease that degrades elastin, fibronectin, laminin, vitronectin, and collagen types I, III, and IV (in vitro) (PubMed:3198760, PubMed:2033050, PubMed:28240246). By cleaving and activating receptor F2RL1/PAR-2, enhances endothelial cell barrier function and thus vascular integrity during neutrophil transendothelial migration (PubMed:23202369). May play a role in neutrophil transendothelial migration, probably when associated with CD177 (PubMed:22266279).[UniProtKB/Swiss-Prot Function]
Species/Host:    HEK293
Molecular Weight:    The protein has a predicted molecular mass of 26.2 kDa after removal of the signal peptide. The apparent molecular mass of PRTN3-His is approximately 25-35 kDa due to glycosylation.
Molecular Characterization:    PRTN3(Ala26-Pro256) 6×His tag
Purity:    The purity of the protein is greater than 85% as determined by SDS-PAGE and Coomassie blue staining.
Formulation & Reconstitution:    Lyophilized from nanodisc solubilization buffer (20 mM Tris-HCl, 150 mM NaCl, pH 8.0). Normally 5% – 8% trehalose is added as protectants before lyophilization.
Storage & Shipping:    Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.

Figure 1. Human PRTN3 Protein, His Tag on SDS-PAGE under reducing condition.
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