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Human S100A4 Protein, hFc Tag

Recombinant Human S100A4 Protein with C-terminal human Fc tag


Cat.#:  11877

   Size:   100 μg

In Stock

          Product Description          
Cat.#:     11877
Product Name:   Human S100A4 Protein
Size :    10 µg, 50 µg and 100 µg
Synonyms:   18A2;42A;CAPL;FSP1;MTS1;P9KA;PEL98
Target:    S100A4
UNIPROT ID:    P26447
Description:    Recombinant Human S100A4 Protein with C-terminal human Fc tag
Background:     The protein encoded by this gene is a member of the S100 family of proteins containing 2 EF-hand calcium-binding motifs. S100 proteins are localized in the cytoplasm and/or nucleus of a wide range of cells, and involved in the regulation of a number of cellular processes such as cell cycle progression and differentiation. S100 genes include at least 13 members which are located as a cluster on chromosome 1q21. This protein may function in motility, invasion, and tubulin polymerization. Chromosomal rearrangements and altered expression of this gene have been implicated in tumor metastasis. Multiple alternatively spliced variants, encoding the same protein, have been identified. [provided by RefSeq, Jul 2008]
Species/Host:    HEK293
Molecular Weight:    The protein has a predicted molecular mass of 37.7 kDa after removal of the signal peptide. The apparent molecular mass of S100A4-hFc is approximately 35-55 kDa due to glycosylation.
Molecular Characterization:    S100A4(Ala2-Lys101) hFc(Glu99-Ala330)
Purity:    The purity of the protein is greater than 95% as determined by SDS-PAGE and Coomassie blue staining.
Formulation & Reconstitution:    Lyophilized from nanodisc solubilization buffer (20 mM Tris-HCl, 150 mM NaCl, pH 8.0). Normally 5% – 8% trehalose is added as protectants before lyophilization.
Storage & Shipping:    Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.

Figure 1. Human S100A4 Protein, hFc Tag on SDS-PAGE under reducing condition.