Cat.#: 11591 |
Product Name: Human SSTR2 Protein |
Size : 10 µg, 50 µg and 100 µg |
Synonyms: SRIF-1;SS2R |
Target: SSTR2 |
UNIPROT ID: P30874 |
Description: Recombinant human SSTR2 protein with C-terminal human Fc tag |
Background: Somatostatin acts at many sites to inhibit the release of many hormones and other secretory proteins. The biologic effects of somatostatin are probably mediated by a family of G protein-coupled receptors that are expressed in a tissue-specific manner. SSTR2 is a member of the superfamily of receptors having seven transmembrane segments and is expressed in highest levels in cerebrum and kidney. [provided by RefSeq, Jul 2008] |
Species/Host: HEK293 |
Molecular Weight: The protein has a predicted molecular mass of 30.9 kDa after removal of the signal peptide. The apparent molecular mass of SSTR2-hFc is approximately 40-55 kDa due to glycosylation. |
Molecular Characterization: SSTR2(Met1-Asn43) hFc(Glu99-Ala330) |
Purity: The purity of the protein is greater than 95% as determined by SDS-PAGE and Coomassie blue staining. |
Formulation & Reconstitution: Lyophilized from nanodisc solubilization buffer (20 mM Tris-HCl, 150 mM NaCl, pH 8.0). Normally 5% – 8% trehalose is added as protectants before lyophilization. |
Storage & Shipping: Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature. |
 Figure 1. Human SSTR2 Protein, hFc Tag on SDS-PAGE under reducing condition. |  Figure 2. ELISA plate pre-coated by 2 µg/ml (100 µl/well) Human SSTR2 Protein, hFc Tag (11591) can bind Anti-SSTR2 Neutralizing antibody 28122 in a linear range of 2.93-187.50 ng/mL. |
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