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$445.00
| Cat.#: 11308 | ||
| Product Name: Human TIGIT Protein | ||
| Size : 10 µg, 50 µg and 100 µg | ||
| Synonyms: TIGIT;SIG9;STM3 | ||
| Target: TIGIT | ||
| UNIPROT ID: Q495A1 | ||
| Description: Recombinant human TIGIT Protein with C-terminal mouse Fc tag | ||
| Background: This gene encodes a member of the PVR (poliovirus receptor) family of immunoglobin proteins. The product of this gene is expressed on several classes of T cells including follicular B helper T cells (TFH). The protein has been shown to bind PVR with high affinity, this binding is thought to assist interactions between TFH and dendritic cells to regulate T cell dependent B cell responses. | ||
| Species/Host: HEK293 | ||
| Molecular Weight: The protein has a predicted molecular mass of 39.24 kDa after removal of the signal peptide.The apparent molecular mass of TIGIT-mFc is approximately 40-53 kDa due to glycosylation. | ||
| Molecular Characterization: TIGIT(Met22-Pro141) mFc(Pro99-Lys330) | ||
| Purity: The purity of the protein is greater than 95% as determined by SDS-PAGE and Coomassie blue staining. | ||
| Formulation & Reconstitution: Lyophilized from nanodisc solubilization buffer (20 mM Tris-HCl, 150 mM NaCl, pH 8.0). Normally 5% – 8% trehalose is added as protectants before lyophilization. | ||
| Storage & Shipping: Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature. | ||
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