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Human TNFRSF10A Protein, hFc Tag

Recombinant human TNFRSF10A protein with C-terminal human Fc tag


Cat.#:  11722

   Size:   100 μg

Under development

          Product Description          
Cat.#:     11722
Product Name:   Human TNFRSF10A Protein
Size :    10 µg, 50 µg and 100 µg
Synonyms:   APO2;CD261;DR4;TRAILR-1;TRAILR1
Target:    TNFRSF10A
UNIPROT ID:    O00220
Description:    Recombinant human TNFRSF10A protein with C-terminal human Fc tag
Background:     The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor is activated by tumor necrosis factor-related apoptosis inducing ligand (TNFSF10/TRAIL), and thus transduces cell death signal and induces cell apoptosis. Studies with FADD-deficient mice suggested that FADD, a death domain containing adaptor protein, is required for the apoptosis mediated by this protein. [provided by RefSeq, Jul 2008]
Species/Host:    HEK293
Molecular Weight:    The protein has a predicted molecular mass of 49.28 kDa after removal of the signal peptide.
Molecular Characterization:    TNFRSF10A (Ala24-Asn239) hFc (Glu99-Ala330)
Purity:    The purity of the protein is greater than 95% as determined by SDS-PAGE and Coomassie blue staining.
Formulation & Reconstitution:    Lyophilized from nanodisc solubilization buffer (20 mM Tris-HCl, 150 mM NaCl, pH 8.0). Normally 5% – 8% trehalose is added as protectants before lyophilization.
Storage & Shipping:    Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.