| Cat.#: 11275 |
| Product Name: Human TweakR Protein |
| Size : 10 µg, 50 µg and 100 µg |
| Synonyms: TNFRSF12A;GF-inducible 14;N14;weakR;D266 |
| Target: TweakR |
| UNIPROT ID: Q9NP84 |
| Description: Recombinant human TweakR protein with C-terminal mouse Fc tag |
| Background: TNFRSF12A (TNF Receptor Superfamily Member 12A) is a Protein Coding gene. Diseases associated with TNFRSF12A include?Multiple Sclerosis?and?Stroke, Ischemic. Among its related pathways are?ERK Signaling?and?CDK-mediated phosphorylation and removal of Cdc6 |
| Species/Host: HEK293 |
| Molecular Weight: The protein has a predicted molecular mass of 31.8 kDa after removal of the signal peptide. |
| Molecular Characterization: TweakR(Glu28-Pro80) mFc(Pro99-Lys330) |
| Purity: The purity of the protein is greater than 90% as determined by SDS-PAGE and Coomassie blue staining. |
| Formulation & Reconstitution: Lyophilized from nanodisc solubilization buffer (20 mM Tris-HCl, 150 mM NaCl, pH 8.0). Normally 5% – 8% trehalose is added as protectants before lyophilization. |
| Storage & Shipping: Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature. |
Figure 1. Human TweakR Protein, mFc Tag on SDS-PAGE under non-reducing (NR) and reducing (R) conditions. | 
Figure 2. ELISA plate pre-coated by 2 µg/ml (100 µl/well) Human TweakR, mFc tagged protein (11275) can bind Anti-TweakR Neutralizing antibody 28040 in a linear range of 0.64-80 ng/ml. |
|
