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Human ULBP2 Protein, hFc Tag

Recombinant human ULBP2 protein with C-terminal human Fc tag


Cat.#:  11742

   Size:   100 μg

Under development

          Product Description          
Cat.#:     11742
Product Name:   Human ULBP2 Protein
Size :    10 µg, 50 µg and 100 µg
Synonyms:   ALCAN-alpha;N2DL2;NKG2DL2;RAET1H;RAET1L
Target:    ULBP2
Description:    Recombinant human ULBP2 protein with C-terminal human Fc tag
Background:     This gene encodes a major histocompatibility complex (MHC) class I-related molecule that binds to the NKG2D receptor on natural killer (NK) cells to trigger release of multiple cytokines and chemokines that in turn contribute to the recruitment and activation of NK cells. The encoded protein undergoes further processing to generate the mature protein that is either anchored to membrane via a glycosylphosphatidylinositol moiety, or secreted. Many malignant cells secrete the encoded protein to evade immunosurveillance by NK cells. This gene is located in a cluster of multiple MHC class I-related genes on chromosome 6. [provided by RefSeq, Jul 2015]
Species/Host:    HEK293
Molecular Weight:    The protein has a predicted molecular mass of 46.53 kDa after removal of the signal peptide.
Molecular Characterization:    ULBP2 (Gly26-Ser216) hFc(Glu99-ALA330)
Purity:    The purity of the protein is greater than 95% as determined by SDS-PAGE and Coomassie blue staining.
Formulation & Reconstitution:    Lyophilized from nanodisc solubilization buffer (20 mM Tris-HCl, 150 mM NaCl, pH 8.0). Normally 5% – 8% trehalose is added as protectants before lyophilization.
Storage & Shipping:    Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.