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M-CSF mAb (Lacnotuzumab)

Anti-M-CSF Monoclonal Antibody (Lacnotuzumab)
5/5

$199.00

Cat.#:  28104

   Size:   100 μg

In Stock

          Product Description          
Cat.#:   28104
Product Name:   Anti-M-CSF(Lacnotuzumab) Monoclonal Antibody
Synonyms:   CSF-1;MCSF
Description:    Anti-M-CSF(lacnotuzumab ) Monoclonal Antibody
Background:    Research grade biosimilar. Not for use in therapeutic or diagnostic procedures for humans or animals.
Applications:    ELISA; Flow Cyt
Recommended Dilutions:    ELISA 1:5000-10000; Flow Cyt 1:100
Host Species:    Humanized
Isotype:    IgG1
Purification:    Purified from cell culture supernatant by affinity chromatography
Species Reactivity:    Human M-CSF
Constituents:    Lyophilized from sterile PBS, pH 7.4. 5 % – 8% trehalose is added as protectants before lyophilization.
Storage & Shipping:    Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing).

Figure 1. ELISA plate pre-coated by 2 µg/mL (100 µl/well) Human M-CSF Protein, His Tag 11369 can bind Anti-M-CSF Neutralizing antibody ( 28104) in a linear range of 2.44-156.25 ng/mL.

Figure 2. ELISA plate pre-coated by 2 µg/mL (100 µl/well) Human M-CSF Protein, hFc Tag (11350) can bind Anti-M-CSF Neutralizing antibody (28104) in a linear range of 9.77-156.25 ng/mL. In order to specifically detect 28104, mouse anti-human Fab-specific antibody was used as detection antibody.

Figure 3.Flow cytometry analysis with 1 µg/mL Anti-M-CSF (lacnotuzumab biosimilar) mAb (28104) on Expi293 cells transfected with Human M-CSF protein (Blue histogram) or Expi293 transfected with irrelevant protein (Red histogram).
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