| Cat.#: 28104 |
| Product Name: Anti-M-CSF(Lacnotuzumab) Monoclonal Antibody |
| Synonyms: CSF-1;MCSF |
| Description: Anti-M-CSF(lacnotuzumab ) Monoclonal Antibody |
| Background: Research grade biosimilar. Not for use in therapeutic or diagnostic procedures for humans or animals. |
| Applications: ELISA; Flow Cyt |
| Recommended Dilutions: ELISA 1:5000-10000; Flow Cyt 1:100 |
| Host Species: Humanized |
| Isotype: IgG1 |
| Purification: Purified from cell culture supernatant by affinity chromatography |
| Species Reactivity: Human M-CSF |
| Constituents: Lyophilized from sterile PBS, pH 7.4. 5 % – 8% trehalose is added as protectants before lyophilization. |
| Storage & Shipping: Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). |
Figure 1. ELISA plate pre-coated by 2 µg/mL (100 µl/well) Human M-CSF Protein, His Tag 11369 can bind Anti-M-CSF Neutralizing antibody ( 28104) in a linear range of 2.44-156.25 ng/mL. | 
Figure 2. ELISA plate pre-coated by 2 µg/mL (100 µl/well) Human M-CSF Protein, hFc Tag (11350) can bind Anti-M-CSF Neutralizing antibody (28104) in a linear range of 9.77-156.25 ng/mL. In order to specifically detect 28104, mouse anti-human Fab-specific antibody was used as detection antibody. | 
Figure 3.Flow cytometry analysis with 1 µg/mL Anti-M-CSF (lacnotuzumab biosimilar) mAb (28104) on Expi293 cells transfected with Human M-CSF protein (Blue histogram) or Expi293 transfected with irrelevant protein (Red histogram). | |
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