Email: info@neweastbio.com   |  Call: 6109452007

LIGHT (DM170) Rabbit mAb

Anti-LIGHT (DM170) Rabbit Monoclonal Antibody
5/5

$445.00

Cat.#:  28513

   Size:   100 μg

In Stock

          Product Description          
Cat.#:   28513
Product Name:   Anti-LIGHT(DM170) Rabbit Monoclonal Antibody
Synonyms:   TNFSF14; CD258; HVEML; LIGHT; LTg
Description:    Anti-LIGHT antibody(DM170) Rabbit Monoclonal Antibody
Background:    The protein encoded by this gene is a member of the tumor necrosis factor (TNF) ligand family. This protein is a ligand for TNFRSF14; which is a member of the tumor necrosis factor receptor superfamily; and which is also known as a herpesvirus entry mediator (HVEM). This protein may function as a costimulatory factor for the activation of lymphoid cells and as a deterrent to infection by herpesvirus. This protein has been shown to stimulate the proliferation of T cells; and trigger apoptosis of various tumor cells. This protein is also reported to prevent tumor necrosis factor alpha mediated apoptosis in primary hepatocyte. Two alternatively spliced transcript variant encoding distinct isoforms have been reported.
Applications:    ELISA; Flow Cyt
Recommended Dilutions:    ELISA 1:5000-10000; Flow Cyt 1:100
Host Species:    Rabbit
Isotype:    Rabbit IgG
Purification:    Purified from cell culture supernatant by affinity chromatography
Species Reactivity:    Human LIGHT
Constituents:    Lyophilized from sterile PBS, pH 7.4. 5 % – 8% trehalose is added as protectants before lyophilization.
Storage & Shipping:    Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing).

Figure 1. Flow cytometry analysis with Anti-LIGHT (DM170) on Expi293 cells transfected with human LIGHT (Blue histogram) or Expi293 transfected with irrelevant protein (Red histogram).
          Publications