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Human MC4R Full Length Protein

Human MC4R Full Length Protein-Synthetic Nanodisc
5/5

$4,400.00

Cat.#:  11103

   Size:   50 μg

In Stock

          Product Description          
Cat.#:     11103
Product Name:   Human MC4R Full Length Protein
Size :    10 µg; 50 µg and 100 µg
Synonyms:   BMIQ20
Target:    MC4R
UNIPROT ID:    P32245
Description:    Human MC4R Full Length Protein-Synthetic Nanodisc
Background:     The protein is a membrane-bound receptor and member of the melanocortin receptor family. The encoded protein interacts with adrenocorticotropic and MSH hormones and is mediated by G proteins. This is an intronless gene. Defects in this gene are a cause of autosomal dominant obesity.
Species/Host:    HEK293
Molecular Weight:    The human full length MC4R protein has a MW of 36.9 kDa
Formulation & Reconstitution:    Lyophilized from nanodisc solubilization buffer (20 mM Tris-HCl, 150 mM NaCl, pH 8.0). Normally 5% – 8% trehalose is added as protectants before lyophilization.
Storage & Shipping:    Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
Protein Families:    Druggable Genome, GPCR, Transmembrane
Protein Pathways:    Neuroactive ligand-receptor interaction

Figure 1. Elisa plates were pre-coated with Flag Tag MC4R-Nanodisc (0.2μg/per well). Serial diluted anti-Flag monoclonal antibody solutions were added, washed, and incubated with secondary antibody before Elisa reading. From above data, the EC50 for anti-Flag monoclonal antibody binding with MC4R-Nanodisc is 1.957ng/ml.

Figure 2. Human MC4R-Nanodisc, Flag Tag on SDS-PAGE
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