| Cat.#: 12125 |
| Product Name: Mouse BCMA Protein |
| Size : 10 µg, 50 µg and 100 µg |
| Synonyms: BCM;BCMA;Tnfrsf13;Tnfrsf13a |
| Target: BCMA |
| UNIPROT ID: O88472 |
| Description: Recombinant mouse BCMA protein with C-terminal human Fc tag |
| Background: Receptor for TNFSF13B/BLyS/BAFF and TNFSF13/APRIL. Promotes B-cell survival and plays a role in the regulation of humoral immunity. Activates NF-kappa-B and JNK (By similarity).[UniProtKB/Swiss-Prot Function] |
| Species/Host: HEK293 |
| Molecular Weight: The protein has a predicted molecular mass of 31.6 kDa after removal of the signal peptide.The apparent molecular mass of mBCMA-hFc is approximately 35-55 kDa due to glycosylation. |
| Molecular Characterization: Mouse BCMA(Met1-Thr49) hFc(Glu99-Ala330) |
| Purity: The purity of the protein is greater than 95% as determined by SDS-PAGE and Coomassie blue staining. |
| Formulation & Reconstitution: Lyophilized from nanodisc solubilization buffer (20 mM Tris-HCl, 150 mM NaCl, pH 8.0). Normally 5% – 8% trehalose is added as protectants before lyophilization. |
| Storage & Shipping: Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature. |
Figure 1. Mouse BCMA Protein, hFc Tag on SDS-PAGE under reducing condition. | 
Figure 2. ELISA plate pre-coated by 1 µg/ml (100 µl/well) Mouse BCMA Protein, hFc Tag (12125) can bind anti BCMA monoclonal antibody 28288 in a linear range of 3.2-400 ng/mL. |
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