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Mouse CB1 Protein, hFc Tag

Recombinant mouse CB1 protein with C-terminal human Fc tag
5/5

$569.00

Cat.#:  12179

   Size:   100 μg

In Stock

          Product Description          
Cat.#:     12179
Product Name:   Mouse CB1 Protein
Size :    10 µg, 50 µg and 100 µg
Synonyms:   Cannabinoid receptor 1;CB-R;Cnr1
Target:    CB1
UNIPROT ID:    P47746
Description:    Recombinant mouse CB1 protein with C-terminal human Fc tag
Background:     This gene encodes one of two cannabinoid receptors. The cannabinoids, principally delta-9-tetrahydrocannabinol and synthetic analogs, are psychoactive ingredients of marijuana. The cannabinoid receptors are members of the guanine-nucleotide-binding protein (G-protein) coupled receptor family, which inhibit adenylate cyclase activity in a dose-dependent, stereoselective and pertussis toxin-sensitive manner. The two receptors have been found to be involved in the cannabinoid-induced CNS effects (including alterations in mood and cognition) experienced by users of marijuana. Multiple transcript variants encoding two different protein isoforms have been described for this gene. [provided by RefSeq, May 2009]
Species/Host:    HEK293
Molecular Weight:    The protein has a predicted molecular mass of 39.4 kDa after removal of the signal peptide. The apparent molecular mass of mCB1-hFc is approximately 40-55 kDa due to glycosylation.
Molecular Characterization:    Mouse CB1(Met1-Leu118) hFc(Glu99-Ala330)
Purity:    The purity of the protein is greater than 95% as determined by SDS-PAGE and Coomassie blue staining.
Formulation & Reconstitution:    Lyophilized from nanodisc solubilization buffer (20 mM Tris-HCl, 150 mM NaCl, pH 8.0). Normally 5% – 8% trehalose is added as protectants before lyophilization.
Storage & Shipping:    Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.

Figure 1. Mouse CB1 Protein, hFc Tag on SDS-PAGE under reducing condition.
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