NewEast Biosciences pioneered the research and development of the antibodies for GTPases and mutated Oncogene ten years ago. GTPases involve (1) signal transduction in response to activation of cell surface receptors, including transmembrane receptors such as those mediating taste, smell and vision, (2) protein biosynthesis at the ribosome, (3) regulation of cell differentiation, proliferation, division and movement, (4) translocation of proteins through membranes, (5) transport of vesicles within the cell, and vesicle-mediated secretion and uptake, through GTPase control of vesicle coat assembly. An oncogene is a gene that has the potential to cause cancer.
We offer three unique categories of antibodies, which (1) recognize only the active configuration of GTPase (not the inactive one), (2) mutated Oncogene (not mild type) and (3) have super affinity for cAMP and cGMP (no acetylation required). We have over one thousand peer reviewed articles cited our products.
$389.00
Cat.#: 12201 |
Product Name: Mouse CD24 Protein |
Size : 10 µg, 50 µg and 100 µg |
Synonyms: CD24a;HSA;Ly-52;nectadrin |
Target: CD24 |
UNIPROT ID: P24807 |
Description: Recombinant mouse CD24 protein with C-terminal human Fc tag |
Background: Enables Hsp70 protein binding activity; Hsp90 protein binding activity; and carbohydrate binding activity. Involved in several processes, including chemokine receptor transport out of membrane raft; negative regulation of cytokine production; and regulation of inflammatory response to wounding. Acts upstream of or within several processes, including positive regulation of immune response; regulation of cell-cell adhesion; and regulation of lymphocyte activation. Located in cell projection membrane; external side of plasma membrane; and membrane raft. Is anchored component of external side of plasma membrane. Is expressed in several structures, including extraembryonic component; genitourinary system; hemolymphoid system; hindlimb; and retina. Human ortholog(s) of this gene implicated in multiple sclerosis. Orthologous to human CD24 (CD24 molecule). [provided by Alliance of Genome Resources, Apr 2022] |
Species/Host: HEK293 |
Molecular Weight: The protein has a predicted molecular mass of 28.8 kDa after removal of the signal peptide. The apparent molecular mass of mCD24-hFc is approximately 35-55 kDa due to glycosylation. |
Molecular Characterization: Mouse CD24(Asn27-Arg52) hFc(Glu99-Ala330) |
Purity: The purity of the protein is greater than 95% as determined by SDS-PAGE and Coomassie blue staining. |
Formulation & Reconstitution: Lyophilized from nanodisc solubilization buffer (20 mM Tris-HCl, 150 mM NaCl, pH 8.0). Normally 5% – 8% trehalose is added as protectants before lyophilization. |
Storage & Shipping: Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature. |
Figure 1. Mouse CD24 Protein, hFc Tag on SDS-PAGE under reducing condition. |