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Mouse GITR Protein, hFc Tag

Recombinant mouse GITR protein with C-terminal human Fc tag
5/5

$389.00

Cat.#:  12140

   Size:   100 μg

In Stock

          Product Description          
Cat.#:     12140
Product Name:   Mouse GITR Protein
Size :    10 µg, 50 µg and 100 µg
Synonyms:   AITR;Gitr
Target:    GITR
UNIPROT ID:    O35714
Description:    Recombinant mouse GITR protein with C-terminal human Fc tag
Background:     Receptor for TNFSF18. Seems to be involved in interactions between activated T-lymphocytes and endothelial cells and in the regulation of T-cell receptor-mediated cell death. Mediated NF-kappa-B activation via the TRAF2/NIK pathway (By similarity).[UniProtKB/Swiss-Prot Function]
Species/Host:    HEK293
Molecular Weight:    The protein has a predicted molecular mass of 40.3 kDa after removal of the signal peptide.The apparent molecular mass of mGITR-hFc is approximately 35-55 kDa due to glycosylation.
Molecular Characterization:    Mouse GITR(Ser22-His153) hFc(Glu99-Ala330)
Purity:    The purity of the protein is greater than 95% as determined by SDS-PAGE and Coomassie blue staining.
Formulation & Reconstitution:    Lyophilized from nanodisc solubilization buffer (20 mM Tris-HCl, 150 mM NaCl, pH 8.0). Normally 5% – 8% trehalose is added as protectants before lyophilization.
Storage & Shipping:    Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.

Figure 1.Mouse GITR Protein, hFc Tag on SDS-PAGE under reducing condition.
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