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Mouse TIGIT Protein, hFc Tag

Recombinant mouse TIGIT protein with C-terminal human Fc tag
5/5

$550.00

Cat.#:  12177

   Size:   100 μg

In Stock

          Product Description          
Cat.#:     12177
Product Name:   Mouse TIGIT Protein
Size :    10 µg, 50 µg and 100 µg
Synonyms:   T-cell immunoreceptor with Ig and ITIM domains;V-set and transmembrane domain-containing protein 3;Vstm3
Target:    TIGIT
UNIPROT ID:    A0A0B4J1G6
Description:    Recombinant mouse TIGIT protein with C-terminal human Fc tag
Background:     This gene encodes a member of the PVR (poliovirus receptor) family of immunoglobin proteins. The product of this gene is expressed on several classes of T cells including follicular B helper T cells (TFH). The protein has been shown to bind PVR with high affinity; this binding is thought to assist interactions between TFH and dendritic cells to regulate T cell dependent B cell responses.[provided by RefSeq, Sep 2009]
Species/Host:    HEK293
Molecular Weight:    The protein has a predicted molecular mass of 38.6 kDa after removal of the signal peptide. The apparent molecular mass of mTIGIT-hFc is approximately 40-55 kDa due to glycosylation.
Molecular Characterization:    Mouse TIGIT(Ile28-Pro139) hFc(Glu99-Ala330)
Purity:    The purity of the protein is greater than 95% as determined by SDS-PAGE and Coomassie blue staining.
Formulation & Reconstitution:    Lyophilized from nanodisc solubilization buffer (20 mM Tris-HCl, 150 mM NaCl, pH 8.0). Normally 5% – 8% trehalose is added as protectants before lyophilization.
Storage & Shipping:    Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.

Figure 1. Mouse TIGIT Protein, hFc Tag on SDS-PAGE under reducing condition.
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