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B7-H5 mAb (Onvatilimab)

Anti-B7-H5 Monoclonal Antibody (OnvatiliMonoclonal Antibody)?


Cat.#:  28108

   Size:   100 μg

In Stock

            Product Description          
Cat.#:   28108
Product Name:   Anti-B7-H5(Onvatilimab) Monoclonal Antibody
Synonyms:   VISTA;VSIR;Sisp-1;C10orf54;DD1alpha;Dies1;GI24;PD-1H;PP2135
Description:    Anti-B7-H5(onvatilimab ) Monoclonal Antibody
Background:    Research grade biosimilar. Not for use in therapeutic or diagnostic procedures for humans or animals.
Applications:    ELISA; Flow Cyt
Recommended Dilutions:    ELISA 1:5000-10000; Flow Cyt 1:100
Host Species:    Homo sapiens
Isotype:    IgG1
Purification:    Purified from cell culture supernatant by affinity chromatography
Species Reactivity:    Human B7-H5
Constituents:    Lyophilized from sterile PBS, pH 7.4. 5 % – 8% trehalose is added as protectants before lyophilization.
Storage & Shipping:    Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing).

Figure 1. ELISA plate pre-coated by 2 µg/mL (100 µl/well) Human B7-H5 Protein, hFc Tag (11729) can bind Anti-B7-H5 Neutralizing antibody (28108) in a linear range of 2.44-625.00 ng/mL. In order to specifically detect 28108, mouse anti-human Fab-specific antibody was used as detection antibody.

Figure 2. Flow cytometry analysis with 1 µg/mL Anti-B7-H5 (onvatilimab biosimilar) mAb (28108) on Expi293 cells transfected with Human B7-H5 protein (Blue histogram) or Expi293 transfected with irrelevant protein (Red histogram).