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OX40 (DM116) Rabbit mAb

Anti-OX40 (DM116) Rabbit Monoclonal Antibody
5/5

$445.00

Cat.#:  28461

   Size:   100 μg

In Stock

          Product Description          
Cat.#:   28461
Product Name:   Anti-OX40(DM116) Rabbit Monoclonal Antibody
Synonyms:   TNFRSF4; OX40; CD134; OX40L receptor; ACT35; TXGP1L
Description:    Anti-OX40 antibody(DM116) Rabbit Monoclonal Antibody
Background:    The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor has been shown to activate NF-kappaB through its interaction with adaptor proteins TRAF2 and TRAF5. Knockout studies in mice suggested that this receptor promotes the expression of apoptosis inhibitors BCL2 and BCL2lL1:BCL2-XL; and thus suppresses apoptosis. The knockout studies also suggested the roles of this receptor in CD4 T cell response; as well as in T cell-dependent B cell proliferation and differentiation.
Applications:    ELISA; Flow Cyt
Recommended Dilutions:    ELISA 1:5000-10000; Flow Cyt 1:100
Host Species:    Rabbit
Isotype:    Rabbit IgG
Purification:    Purified from cell culture supernatant by affinity chromatography
Species Reactivity:    Human OX40
Constituents:    Lyophilized from sterile PBS, pH 7.4. 5 % – 8% trehalose is added as protectants before lyophilization.
Storage & Shipping:    Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing).

Figure 1. ELISA plate pre-coated by 2 µg/ml (100 µl/well) Human OX40 protein, hFc-His tagged protein 11150 can bind Rabbit anti-OX40 monoclonal antibody  (clone: DM116) in a linear range of 6-70 ng/ml.

Figure 2. Flow cytometry analysis with Anti-OX40  (DM116) on Expi293 cells transfected with human OX40 (Blue histogram) or Expi293 transfected with irrelevant protein(Red histogram).
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