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Human PTGDR2 Full Length Protein

Human PTGDR2 Full Length Protein-Synthetic Nanodisc
5/5

$4,400.00

Cat.#:  11106

   Size:   50 μg

In Stock

          Product Description          
Cat.#:     11106
Product Name:   Human PTGDR2 Full Length Protein
Size :    10 µg; 50 µg and 100 µg
Synonyms:   CD294; CRTH2; DL1R; DP2; GPR44
Target:    PTGDR2
UNIPROT ID:    Q9Y5Y4
Description:    Human PTGDR2 Full Length Protein-Synthetic Nanodisc
Background:     The protein is a G-protein-coupled receptor that is preferentially expressed in CD4+ effector T helper 2 (Th2) cells. This protein is a prostaglandin D2 receptor that mediates the pro-inflammatory chemotaxis of eosinophils, basophils, and Th2 lymphocytes generated during allergic inflammation. Single nucleotide polymorphisms in the 3' UTR of this gene have been associated with asthma susceptibility.
Species/Host:    HEK293
Molecular Weight:    The human full length PTGDR2 protein has a MW of 43.3 kDa
Formulation & Reconstitution:    Lyophilized from nanodisc solubilization buffer (20 mM Tris-HCl, 150 mM NaCl, pH 8.0). Normally 5% – 8% trehalose is added as protectants before lyophilization.
Storage & Shipping:    Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
Protein Families:    Druggable Genome, GPCR, Transmembrane
Protein Pathways:    N/A

Figure 1. Elisa plates were pre-coated with Flag Tag PTGDR2-Nanodisc (0.2μg/per well). Serial diluted anti-Flag monoclonal antibody solutions were added, washed, and incubated with secondary antibody before Elisa reading. From above data, the EC50 for anti-Flag monoclonal antibody binding with PTGDR2-Nanodisc is 3.249ng/ml.

Figure 2. Human PTGDR2-Nanodisc, Flag Tag on SDS-PAGE
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