NewEast Biosciences pioneered the research and development of the antibodies for GTPases and mutated Oncogene ten years ago. GTPases involve (1) signal transduction in response to activation of cell surface receptors, including transmembrane receptors such as those mediating taste, smell and vision, (2) protein biosynthesis at the ribosome, (3) regulation of cell differentiation, proliferation, division and movement, (4) translocation of proteins through membranes, (5) transport of vesicles within the cell, and vesicle-mediated secretion and uptake, through GTPase control of vesicle coat assembly. An oncogene is a gene that has the potential to cause cancer.
We offer three unique categories of antibodies, which (1) recognize only the active configuration of GTPase (not the inactive one), (2) mutated Oncogene (not mild type) and (3) have super affinity for cAMP and cGMP (no acetylation required). We have over one thousand peer reviewed articles cited our products.
$219.00
Cat. #: 21050 |
Gene Symbol: RAB18 |
Description: Anti-Rab18 Rabbit Polyclonal Antibody |
Background: Rab18 is a member of the Ras-related small GTPases. Rab18 plays a role in apical endocytosis/recycling. |
Immunogen: A synthetic peptide from the C-terminal end of human Rab18 protein |
Applications: ELISA, WB, IHC |
Recommended Dilutions: ELISA: 1:100-1:5000 WB: 1:100-1:2000 IHC: 1:100-1:1000 |
Concentration: 0.2 mg/ml |
Host Species: Rabbit |
Format: Liquid |
Clonality: Polyclonal |
Purity: Purified from serum |
Preservative: no |
Constituents: PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 50% glycerol |
Species Reactivity: Rab18 antibody recognizes Rab18 proteins from vertebrates. |
Storage Conditions: Store at -20°C. Avoid repeated freezing and thawing |
Western blot: EC-1 (lane 1) , HepG (lane 2) and HEK-293T (lane 3) whole-cell lysates were used for Western blots with anti Rab18 polyclonal antibody (cat # 21050). |