NewEast Biosciences pioneered the research and development of the antibodies for GTPases and mutated Oncogene ten years ago. GTPases involve (1) signal transduction in response to activation of cell surface receptors, including transmembrane receptors such as those mediating taste, smell and vision, (2) protein biosynthesis at the ribosome, (3) regulation of cell differentiation, proliferation, division and movement, (4) translocation of proteins through membranes, (5) transport of vesicles within the cell, and vesicle-mediated secretion and uptake, through GTPase control of vesicle coat assembly. An oncogene is a gene that has the potential to cause cancer.
We offer three unique categories of antibodies, which (1) recognize only the active configuration of GTPase (not the inactive one), (2) mutated Oncogene (not mild type) and (3) have super affinity for cAMP and cGMP (no acetylation required). We have over one thousand peer reviewed articles cited our products.
$219.00
Rab6A
Cat. #: 21068 |
Gene Symbol: RAB6A |
Description: Anti-Rab6A Rabbit Polyclonal Antibody |
Background: The small GTPase Rab6 regulates vesicle trafficking at the level of Golgi. There are three forms of Rab6: Rab6A, Rab6A’ (also called Rab6C) and Rab6B. Rab6A and Rab6C are splice variants of the same gene. Rab6A is localized in the Golgi and regulates a COPI-independent pathway of retrograde membrane transport from the Golgi complex to the endoplasmic reticulum. |
Immunogen: A synthetic peptide from the internal region of huamn Rab6A protein |
Applications: ELISA, WB, IHC |
Recommended Dilutions: ELISA 1:100-1:5000 WB 1:100-1:1000 IHC 1:100-1:1000 |
Concentration: 0.2 mg/ml |
Host Species: Rabbit |
Format: Liquid |
Clonality: Polyclonal |
Isotype: IgG |
Purity: Purified from serum |
Preservative: No |
Constituents: PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 50% glycerol |
Species Reactivity: Rab6A antibody recognizes Rab6A proteins from vertebrates. |
Storage Conditions: Store at -20°C. Avoid repeated freezing and thawing |
Western blot: HEK-293T (lane 1) and MEF (lane 2) whole-cell extracts were used for Western blot with anti Rab6A polyclonal antibody (cat # 21068). |