NewEast Biosciences pioneered the research and development of the antibodies for GTPases and mutated Oncogene ten years ago. GTPases involve (1) signal transduction in response to activation of cell surface receptors, including transmembrane receptors such as those mediating taste, smell and vision, (2) protein biosynthesis at the ribosome, (3) regulation of cell differentiation, proliferation, division and movement, (4) translocation of proteins through membranes, (5) transport of vesicles within the cell, and vesicle-mediated secretion and uptake, through GTPase control of vesicle coat assembly. An oncogene is a gene that has the potential to cause cancer.
We offer three unique categories of antibodies, which (1) recognize only the active configuration of GTPase (not the inactive one), (2) mutated Oncogene (not mild type) and (3) have super affinity for cAMP and cGMP (no acetylation required). We have over one thousand peer reviewed articles cited our products.
$219.00
Rab7A Polyclonal Antibody
Cat. #: 21069 |
Gene Symbol: RAB7A |
Description: Anti-Rab7A Rabbit Polyclonal Antibody |
Background: Rab7A belongs to the Rab family of small GTPases. Rab7A is located in the late endosome, lysosome, cytoplasmic vesicle, phagosome and melanosome. It is involved in the late endocytic transport and contributes to the maturation of phagosomes. |
Immunogen: A synthetic peptide near the C-terminus of Rab7A of human origin. |
Applications: ELISA, WB, IHC, IP |
Recommended Dilutions: ELISA: 1:100-1:5000 WB: 1:100-1:2000 IHC: 1:10-1:100 |
Concentration: 0.2 mg/ml |
Host Species: Rabbit |
Format: Liquid |
Clonality: Polyclonal |
Purity: Purified from serum |
Preservative: No |
Constituents: PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 50% glycerol |
Species Reactivity: Rab7A antibody recognizes Rab7A from vertebrates. |
Storage Conditions: Store at -20°C. Avoid repeated freezing and thawing |
Western blot: Purified recombinant His-tagged Rab7A protein (lane 1, Cat # 10167), MEF (lane 2), HEK293 (lane 3) and NIH 3T3 (lane 4) cell lysates were used for Western blot with anti Rab7A polyclonal antibody (Cat # 21069). |