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RheB mAb

 Anti-RheB Mouse Monoclonal Antibody
5/5

$239.00

Cat.#:  26015

   Size:   100 μl

In Stock

          Product Description          

RheB Monoclonal Antibody

Cat. #:  26015
Gene Symbol:  RHEB
Description:   Anti-RheB Mouse Monoclonal Antibody
Background:   RheB (Ras Homolog Enriched in Brain) is an evolutionarily conserved member of the Ras-family of small GTP-binding proteins originally found to be rapidly induced by synaptic activity in the hippocampus following seizure. While it is expressed at relatively high levels in the brain, RheB is widely expressed in other tissues and may be induced by growth factor stimulation. RheB has an important role in regulating the insulin/TOR signaling pathway. The mammalian target of rapamycin, mTOR, is a serine/threonine protein kinase that acts as a sensor for ATP and amino acids, balancing the availability of nutrients with translation and cell growth. The tuberin/hamartin (TSC2/TSC1) complex inhibits mTOR activity indirectly by inhibiting RheB via tuberin’s GAP activity.
Immunogen:   Recombinant full length protein of RheB.
Applications:   ELISA, WB, IHC
Recommended Dilutions:   
ELISA: 1:100-1:5000
WB: 1:100-1:2000
IHC: 1:50-1:100
Concentration:   1 mg/ml
Host Species:   Mouse
Format:   Liquid
Clonality:   Monoclonal
Isotype:   IgG
Purity:   Purified from ascites
Preservative: No
Constituents:   PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 50% glycerol
Species Reactivity:  RheB antibody recognizes RheB proteins of vertebrates.
Storage Conditions:  Store at -20°C. Avoid repeated freezing and thawing

Western blot:  

Western blot analysis of RheB proteins. HEK-293 whole-cell lysate was used for Western blot.

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