Subtotal:
$445.00
$445.00
| Cat.#: 28403 | ||
| Product Name: Anti-TIM3(DM81) Rabbit Monoclonal Antibody | ||
| Synonyms: HAVCR2; TIM3; TIMD3; FLJ14428; KIM3 | ||
| Description: Anti-TIM3 antibody(DM81) Rabbit Monoclonal Antibody | ||
| Background: The protein encoded by this gene belongs to the immunoglobulin superfamily; and TIM family of proteins. CD4-positive T helper lymphocytes can be divided into types 1 (Th1) and 2 (Th2) on the basis of their cytokine secretion patterns. Th1 cells are involved in cell-mediated immunity to intracellular pathogens and delayed-type hypersensitivity reactions; whereas; Th2 cells are involved in the control of extracellular helminthic infections and the promotion of atopic and allergic diseases. This protein is a Th1-specific cell surface protein that regulates macrophage activation; and inhibits Th1-mediated auto- and alloimmune responses; and promotes immunological tolerance. | ||
| Applications: ELISA; Flow Cyt | ||
| Recommended Dilutions: ELISA 1:5000-10000; Flow Cyt 1:100 | ||
| Host Species: Rabbit | ||
| Isotype: Rabbit IgG | ||
| Purification: Purified from cell culture supernatant by affinity chromatography | ||
| Species Reactivity: Human TIM3 | ||
| Constituents: Lyophilized from sterile PBS, pH 7.4. 5 % – 8% trehalose is added as protectants before lyophilization. | ||
| Storage & Shipping: Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). | ||
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