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VWF (DMC389) IgG1 Chimeric mAb

Anti-VWF (DMC389) IgG1 Chimeric Monoclonal Antibody


Cat.#:  28207

   Size:   100 μg

In Stock

          Product Description          
Cat.#:   28207
Product Name:   Anti-VWF(DMC389) IgG1 Chimeric Monoclonal Antibody
Synonyms:   F8VWF; VWD
Description:    Anti-VWF antibody(DMC389) IgG1 Chimeric Monoclonal Antibody
Background:    This gene encodes a glycoprotein involved in hemostasis. The encoded preproprotein is proteolytically processed following assembly into large multimeric complexes. These complexes function in the adhesion of platelets to sites of vascular injury and the transport of various proteins in the blood. Mutations in this gene result in von Willebrand disease; an inherited bleeding disorder. An unprocessed pseudogene has been found on chromosome 22.
Applications:    Flow Cyt
Recommended Dilutions:    Flow Cyt 1:100
Host Species:    Rabbit
Isotype:    Rabbit:Human Fc chimeric IgG1
Purification:    Purified from cell culture supernatant by affinity chromatography
Species Reactivity:    Human VWF
Constituents:    Lyophilized from sterile PBS, pH 7.4. 5 % – 8% trehalose is added as protectants before lyophilization.
Storage & Shipping:    Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing).

Figure 1. Flow cytometry analysis with Anti-VWF (DMC389) on Expi293 cells transfected with human VWF (Blue histogram) or Expi293 transfected with irrelevant protein (Red histogram), and  Isotype antibody on Expi293 transfected with irrelevant protein (Orange histogram).