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Human CX3CR1 Full Length Protein

Human CX3CR1 Full Length Protein-Synthetic Nanodisc
5/5

$4,400.00

Cat.#:  11096

   Size:   50 μg

In Stock

          Product Description          
Cat.#:     11096
Product Name:   Human CX3CR1 Full Length Protein
Size :    10 µg; 50 µg and 100 µg
Synonyms:   CCRL1; CMKBRL1; CMKDR1; GPR13; GPRV28; V28
Target:    CX3CR1
UNIPROT ID:    P49238
Description:    Human CX3CR1 Full Length Protein-Synthetic Nanodisc
Background:     Fractalkine is a transmembrane protein and chemokine involved in the adhesion and migration of leukocytes. The protein encoded by this gene is a receptor for fractalkine. The encoded protein also is a coreceptor for HIV-1, and some variations in this gene lead to increased susceptibility to HIV-1 infection and rapid progression to AIDS.
Species/Host:    HEK293
Molecular Weight:    The human full length CX3CR1 protein has a MW of 40.4 kDa
Formulation & Reconstitution:    Lyophilized from nanodisc solubilization buffer (20 mM Tris-HCl, 150 mM NaCl, pH 8.0). Normally 5% – 8% trehalose is added as protectants before lyophilization.
Storage & Shipping:    Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
Protein Families:    Druggable Genome, GPCR, Transmembrane
Protein Pathways:    Chemokine signaling pathway, Cytokine-cytokine receptor interaction

Figure 1. Elisa plates were pre-coated with Flag Tag CX3CR1-Nanodisc (0.2μg/per well). Serial diluted anti-Flag monoclonal antibody solutions were added, washed, and incubated with secondary antibody before Elisa reading. From above data, the EC50 for anti-Flag monoclonal antibody binding with CX3CR1-Nanodisc is 2.796ng/ml.

Figure 2. Human CX3CR1-Nanodisc, Flag Tag on SDS-PAGE
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