$219.00
Ga<sub>13</sub> Polyclonal Antibody
| Cat. #: 21020 |
| Gene Symbol: GNA13 |
| Description: Anti-Ga13Rabbit Polyclonal Antibody |
| Background: Heterotrimeric G proteins are essential cellular signal transducers. Gα13 is one of the G proteins that could mediate cell migration and angiogenesis. Other biochemical and physiological functions of Ga13 are being explored. |
| Immunogen: A synthetic peptide from a unique region of Ga13 |
| Applications: ELISA, WB, IHC |
| Recommended Dilutions: ELISA: 1:100-1:5000 WB: 1:100-1:2000 IHC: 1:50-1:100 |
| Concentration: 0.2 mg/ml |
| Host Species: Rabbit |
| Format: Liquid |
| Clonality: Polyclonal |
| Purity: Purified from serum |
| Preservative: No |
| Constituents: PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 50% glycerol |
| Species Reactivity: Gα13 polyclonal antibody recognizes Gα13 of vertebrates. |
| Storage Conditions: Store at -20°C. Avoid repeated freezing and thawing |
Western blot: Purified Gα13 protein was blot with Anti-Gα13 polyclonal antibody (Cat # 21020). |
| 1. Resistance to inhibitors of cholinesterase-8A (Ric-8A) is critical for growth factor receptor-induced actin cytoskeletal reorganization J Biol Chem. 2011 Sep 2;286(35):31055-61 |
| 2. Agonist activation of the G protein-coupled receptor GPR35 involves transmembrane domain III and is transduced via Galpha and beta-arrestin-2 Br J Pharmacol. 2011 Feb;162(3):733-48 |
| 3. Gα12/13 inhibition enhances the anti-cancer effect of bortezomib through PSMB5 downregulation Carcinogenesis (2010) |
| 4. Suppression of tumor angiogenesis by Galpha(13) haploinsufficiency J Biol Chem. 2009 Oct 2;284(40):27409-15 |
