NewEast Biosciences pioneered the research and development of the antibodies for GTPases and mutated Oncogene ten years ago. GTPases involve (1) signal transduction in response to activation of cell surface receptors, including transmembrane receptors such as those mediating taste, smell and vision, (2) protein biosynthesis at the ribosome, (3) regulation of cell differentiation, proliferation, division and movement, (4) translocation of proteins through membranes, (5) transport of vesicles within the cell, and vesicle-mediated secretion and uptake, through GTPase control of vesicle coat assembly. An oncogene is a gene that has the potential to cause cancer.
We offer three unique categories of antibodies, which (1) recognize only the active configuration of GTPase (not the inactive one), (2) mutated Oncogene (not mild type) and (3) have super affinity for cAMP and cGMP (no acetylation required). We have over one thousand peer reviewed articles cited our products.
$389.00
Cat.#: 12205 |
Product Name: Mouse SEZ6 Protein |
Size : 10 µg, 50 µg and 100 µg |
Synonyms: BSRPC |
Target: SEZ6 |
UNIPROT ID: Q7TSK2 |
Description: Recombinant mouse SEZ6 protein with C-terminal 6xHis tag |
Background: Acts upstream of or within several processes, including excitatory postsynaptic potential; nervous system development; and regulation of dendrite development. Located in several cellular components, including dendrite; neuronal cell body; and perinuclear region of cytoplasm. Is expressed in several structures, including central nervous system; genitourinary system; liver; retina; and thymus. Orthologous to human SEZ6 (seizure related 6 homolog). [provided by Alliance of Genome Resources, Apr 2022] |
Species/Host: HEK293 |
Molecular Weight: The protein has a predicted molecular mass of 98.7 kDa after removal of the signal peptide. The apparent molecular mass of mSEZ6-His is approximately 130-250 kDa due to glycosylation. |
Molecular Characterization: Mouse SEZ6(Leu20-His922) 6×His tag |
Purity: The purity of the protein is greater than 85% as determined by SDS-PAGE and Coomassie blue staining. |
Formulation & Reconstitution: Lyophilized from nanodisc solubilization buffer (20 mM Tris-HCl, 150 mM NaCl, pH 8.0). Normally 5% – 8% trehalose is added as protectants before lyophilization. |
Storage & Shipping: Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature. |
Figure 1. Mouse SEZ6 Protein, His Tag on SDS-PAGE under reducing condition. |