NewEast Biosciences pioneered the research and development of the antibodies for GTPases and mutated Oncogene ten years ago. GTPases involve (1) signal transduction in response to activation of cell surface receptors, including transmembrane receptors such as those mediating taste, smell and vision, (2) protein biosynthesis at the ribosome, (3) regulation of cell differentiation, proliferation, division and movement, (4) translocation of proteins through membranes, (5) transport of vesicles within the cell, and vesicle-mediated secretion and uptake, through GTPase control of vesicle coat assembly. An oncogene is a gene that has the potential to cause cancer.
We offer three unique categories of antibodies, which (1) recognize only the active configuration of GTPase (not the inactive one), (2) mutated Oncogene (not mild type) and (3) have super affinity for cAMP and cGMP (no acetylation required). We have over one thousand peer reviewed articles cited our products.
$219.00
Rab2A Polyclonal Antibody
Cat. #: 21039 |
Gene Symbol: RAB2A |
Description: Anti-Rab2A Rabbit Polyclonal Antibody |
Background: Rab2 is one of the Rab family of proteins that participate in compartment specific transport events of both the endocytic and the exocytic pathways through recruitment and interaction with effectors molecules. Rab2 is highly expressed in the nervous system. Rab2 is essential for membrane trafficking in the early secretory pathway. Rab2 associates with vesicular tubular clusters located between the endoplasmic reticulum and the Golgi complex. |
Immunogen: A synthetic peptide from the N-terminal region of human Rab2A |
Applications: ELISA, WB, IHC |
Recommended Dilutions: ELISA: 1:100-1:5000 WB: 1:100-1:2000 IHC: 1:100-1:1000 |
Concentration: 0.2 mg/ml |
Host Species: Rabbit |
Format: Liquid |
Clonality: Polyclonal |
Purity: Purified from serum |
Preservative: No |
Constituents: PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 50% glycerol |
Species Reactivity: Rab2A antibody recognizes Rab2A from vertebrates. |
Storage Conditions: Store at -20°C. Avoid repeated freezing and thawing |
Western blot: HepG2 (lane 1) and HEK-293T (lane 2) cell lysates were used for Western blot with anti Rab2A polyclonal antibody (cat # 21039). |