NewEast Biosciences pioneered the research and development of the antibodies for GTPases and mutated Oncogene ten years ago. GTPases involve (1) signal transduction in response to activation of cell surface receptors, including transmembrane receptors such as those mediating taste, smell and vision, (2) protein biosynthesis at the ribosome, (3) regulation of cell differentiation, proliferation, division and movement, (4) translocation of proteins through membranes, (5) transport of vesicles within the cell, and vesicle-mediated secretion and uptake, through GTPase control of vesicle coat assembly. An oncogene is a gene that has the potential to cause cancer.
We offer three unique categories of antibodies, which (1) recognize only the active configuration of GTPase (not the inactive one), (2) mutated Oncogene (not mild type) and (3) have super affinity for cAMP and cGMP (no acetylation required). We have over one thousand peer reviewed articles cited our products.
$349.00
Cat.#: S213403 | ||||
Product Name: Anti-POU2AF1 Rabbit Polyclonal Antibody | ||||
Synonyms: BOB1, OBF1, OCAB, OBF-1 | ||||
UNIPROT ID: Q16633 (Gene Accession – NP_006226 ) | ||||
Background: POU domain class 2-associating factor 1 is a protein that in humans is encoded by the POU2AF1 gene. POU2AF1 has been shown to interact with POU2F1 and SIAH1. POU domain class 2-associating factor 1 is a protein that in humans is encoded by the POU2AF1 gene.Transcriptional coactivator that specifically associates with either OCT1 or OCT2. It encourages the OCT1 mediated promoter activity and to a lesser extent, that of OCT2. It has no intrinsic DNA-binding activity. It recognizes the POU domains of OCT1 and OCT2. It is necessary for the response of B-cells to antigens and required for the formation of germinal centers. | ||||
Immunogen: Synthetic peptide of human POU2AF1 | ||||
Applications: ELISA, IHC | ||||
Recommended Dilutions: IHC: Oct-50; ELISA: 1000-2000 | ||||
Host Species: Rabbit | ||||
Clonality: Rabbit Polyclonal | ||||
Isotype: Immunogen-specific rabbit IgG | ||||
Purification: Antigen affinity purification | ||||
Species Reactivity: Human, Mouse | ||||
Constituents: PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.05% Sodium Azide and 40% glycerol | ||||
Research Areas: Epigenetics and Nuclear Signaling, Immunology | ||||
Storage & Shipping: Store at -20°C. Avoid repeated freezing and thawing | ||||
|