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E2F3 Rabbit pAb

Anti-E2F3 Rabbit Polyclonal Antibody
5/5

$349.00

Cat.#:  S215094

   Size:   100 μl

In Stock

          Product Description          
Cat.#:   S215094
Product Name:   Anti-E2F3 Rabbit Polyclonal Antibody
Synonyms:   E2F-3
UNIPROT ID:   O00716 (Gene Accession – NP_001940 )
Background:    This gene encodes a member of a small family of transcription factors that function through binding of DP interaction partner proteins. The encoded protein recognizes a specific sequence motif in DNA and interacts directly with the retinoblastoma protein (pRB) to regulate the expression of genes involved in the cell cycle. Altered copy number and activity of this gene have been observed in a number of human cancers. There are pseudogenes for this gene on chromosomes 2 and 17. Alternative splicing results in multiple transcript variants.
Immunogen:    Synthetic peptide of human E2F3
Applications:    ELISA, IHC
Recommended Dilutions:    IHC: 25-100; ELISA: 5000-10000
Host Species:    Rabbit
Clonality:    Rabbit Polyclonal
Isotype:    Immunogen-specific rabbit IgG
Purification:    Antigen affinity purification
Species Reactivity:    Human, Mouse
Constituents:    PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.05% Sodium Azide and 40% glycerol
Research Areas:    Epigenetics and Nuclear Signaling
Storage & Shipping:    Store at -20°C. Avoid repeated freezing and thawing

Immunohistochemistry analysis of paraffin embedded Human breast cancer tissue using 215094(E2F3 Antibody) at a dilution of 1/20(Nucleus).

In comparision with the IHC on the left, the same paraffin-embedded Human breast cancer tissue is first treated with the synthetic peptide and then with 215094(Anti-E2F3 Antibody) at dilution 1/20.
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