Email: info@neweastbio.com   |  Call: 6109452007

ELOC Rabbit pAb

Anti-ELOC Rabbit Polyclonal Antibody
5/5

$349.00

Cat.#:  S217885

   Size:   100 μl

In Stock

          Product Description          
Cat.#:   S217885
Product Name:   Anti-ELOC Rabbit Polyclonal Antibody
Synonyms:   SIII; TCEB1
UNIPROT ID:   Q15369 (Gene Accession – BC013809 )
Background:    This gene encodes the protein elongin C, which is a subunit of the transcription factor B (SIII) complex. The SIII complex is composed of elongins A/A2, B and C. It activates elongation by RNA polymerase II by suppressing transient pausing of the polymerase at many sites within transcription units. Elongin A functions as the transcriptionally active component of the SIII comple,x whereas elongins B and C are regulatory subunits. Elongin A2 is specifically expressed in the testis, and capable of forming a stable complex with elongins B and C. The von Hippel-Lindau tumor suppressor protein binds to elongins B and C, and thereby inhibits transcription elongation. Multiple alternatively spliced transcript variants encoding two distinct isoforms have been identified.
Immunogen:    Fusion protein of human ELOC
Applications:    ELISA, IHC
Recommended Dilutions:    IHC: 30-150; ELISA: 2000-10000
Host Species:    Rabbit
Clonality:    Rabbit Polyclonal
Isotype:    Immunogen-specific rabbit IgG
Purification:    Antigen affinity purification
Species Reactivity:    Human, Mouse, Rat
Constituents:    PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.05% Sodium Azide and 40% glycerol
Research Areas:    Epigenetics and Nuclear Signaling
Storage & Shipping:    Store at -20°C. Avoid repeated freezing and thawing

Immunohistochemistry analysis of paraffin embedded Human lung cancer tissue using 217885(ELOC Antibody) at a dilution of 1/40(Nucleus).

In comparision with the IHC on the left, the same paraffin-embedded Human lung cancer tissue is first treated with the fusion protein and then with 217885(Anti-ELOC Antibody) at dilution 1/40.
          Publications