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ARMC8 Rabbit pAb

Anti-ARMC8 Rabbit Polyclonal Antibody
5/5

$349.00

Cat.#:  S218669

   Size:   100 μl

In Stock

          Product Description          
Cat.#:   S218669
Product Name:   Anti-ARMC8 Rabbit Polyclonal Antibody
Synonyms:   GID5; VID28; S863-2; HSPC056
UNIPROT ID:   Q8IUR7 (Gene Accession – BC013424 )
Background:    The armadillo (ARM) repeat family of proteins are related to the Drosophila melanogaster armadillo protein, a protein essential for wingless signal transduction. ARM proteins are involved in a variety of processes such as cell migration, cell proliferation, tissue maintenance and tumorigenesis, and they also function in signal transduction and the maintenance of overall cell structure. ARMC8 (armadillo repeat containing 8), also known as S863-2, is a 673 amino acid protein that contains 14 ARM repeats, suggesting a role in signal transduction events throughout the cell. Six isoforms of ARMC8 are expressed due to alternative splicing events. The gene encoding ARMC8 maps to human chromosome 3, which houses over 1,100 genes, including a chemokine receptor (CKR) gene cluster and a variety of human cancer-related gene loci.
Immunogen:    Fusion protein of human ARMC8
Applications:    ELISA, IHC
Recommended Dilutions:    IHC: 40-200; ELISA: 5000-10000
Host Species:    Rabbit
Clonality:    Rabbit Polyclonal
Isotype:    Immunogen-specific rabbit IgG
Purification:    Antigen affinity purification
Species Reactivity:    Human, Mouse
Constituents:    PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.05% Sodium Azide and 40% glycerol
Research Areas:    Epigenetics and Nuclear Signaling
Storage & Shipping:    Store at -20°C. Avoid repeated freezing and thawing

Immunohistochemistry analysis of paraffin embedded Human esophagus cancer tissue using 218669(ARMC8 Antibody) at a dilution of 1/40(Cytoplasm and Nucleus).

In comparision with the IHC on the left, the same paraffin-embedded Human esophagus cancer tissue is first treated with the fusion protein and then with 218669(Anti-ARMC8 Antibody) at dilution 1/40.

The image on the left is immunohistochemistry of paraffin-embedded Human thyroid cancer tissue using 218669(Anti-ARMC8 Antibody) at a dilution of 1/40.

In comparision with the IHC on the left, the same paraffin-embedded Human thyroid cancer tissue is first treated with fusion protein and then with D224914(Anti-ARMC8 Antibody) at dilution 1/40.
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