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KMT2B Rabbit pAb

Anti-KMT2B Rabbit Polyclonal Antibody
5/5

$349.00

Cat.#:  S221308

   Size:   100 μl

In Stock

          Product Description          
Cat.#:   S221308
Product Name:   Anti-KMT2B Rabbit Polyclonal Antibody
Synonyms:   HRX2; MLL2; MLL4; TRX2; WBP7; MLL1B; WBP-7; CXXC10
UNIPROT ID:   Q9UMN6 (Gene Accession – NP_055542 )
Background:    This gene encodes a protein which contains multiple domains including a CXXC zinc finger, three PHD zinc fingers, two FY-rich domains, and a SET (suppressor of variegation, enhancer of zeste, and trithorax) domain. The SET domain is a conserved C-terminal domain that characterizes proteins of the MLL (mixed-lineage leukemia) family. This gene is ubiquitously expressed in adult tissues. It is also amplified in solid tumor cell lines, and may be involved in human cancer. Two alternatively spliced transcript variants encoding distinct isoforms have been reported for this gene, however, the full length nature of the shorter transcript is not known.
Immunogen:    Synthetic peptide of human KMT2B
Applications:    ELISA, IHC
Recommended Dilutions:    IHC: 25-100; ELISA: 5000-10000
Host Species:    Rabbit
Clonality:    Rabbit Polyclonal
Isotype:    Immunogen-specific rabbit IgG
Purification:    Antigen affinity purification
Species Reactivity:    Human, Mouse
Constituents:    PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.05% Sodium Azide and 40% glycerol
Research Areas:    Epigenetics and Nuclear Signaling
Storage & Shipping:    Store at -20°C. Avoid repeated freezing and thawing

Immunohistochemistry analysis of paraffin embedded Human tonsil tissue using 221308(KMT2B Antibody) at a dilution of 1/20(Nucleus).

In comparision with the IHC on the left, the same paraffin-embedded Human tonsil tissue is first treated with the synthetic peptide and then with 221308(Anti-KMT2B Antibody) at dilution 1/20.
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