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PKC beta 2 Rabbit mAb

Anti-PKC beta 2 Rabbit Monoclonal Antibody
5/5

$349.00

Cat.#:  N263617

   Size:   100 μl

In Stock

          Product Description          
Cat.#:   N263617
Product Name:   Anti-PKC beta 2 Rabbit Monoclonal Antibody
Synonyms:   PRKCB; PKCB; PRKCB1; Protein kinase C beta type; PKC-B; PKC-beta
UNIPROT ID:   P05771
Background:    Calcium-activated, phospholipid- and diacylglycerol (DAG)-dependent serine/threonine-protein kinase involved in various cellular processes such as regulation of the B-cell receptor (BCR) signalosome, oxidative stress-induced apoptosis, androgen receptor-dependent transcription regulation, insulin signaling and endothelial cells proliferation. Plays a key role in B-cell activation by regulating BCR-induced NF-kappa-B activation. Mediates the activation of the canonical NF-kappa-B pathway (NFKB1) by direct phosphorylation of CARD11/CARMA1 at ‘Ser-559’, ‘Ser-644’ and ‘Ser-652’.
Immunogen:    A synthesized peptide derived from human PKC beta 2
Applications:    WB,IHC-F,IHC-P,ICC/IF,IP
Recommended Dilutions:    WB: 1/500-1/1000 IHC: 1/50-1/100 IF: 1/50-1/200 IP: 1/20
Host Species:    Rabbit
Clonality:    Rabbit Monoclonal
Clone ID:    R06-0C2
MW:    Calculated MW: 77 kDa; Observed MW: 77 kDa
Isotype:    IgG
Purification:    Affinity Purified
Species Reactivity:    Human,Rat
Conjugation:    Unconjugated
Modification:    Unmodified
Constituents:    PBS (without Mg2+ and Ca2+), pH 7.3 containing 50% glycerol, 0.5% BSA and 0.02% sodium azide
Research Areas:    Signal Transduction
Storage & Shipping:    Store at -20°C. Avoid repeated freezing and thawing

Western blot analysis of PKC beta 2 in Hela, A549, U2OS, U87-MG lysates using PKC beta 2 antibody

Immunocytochemistry analysis of PKC beta 2 (green) in K562 using PKC beta 2 antibody,and DAPI(blue).

Western blot analysis of PKC beta 2 in rat brain lysates using PKC beta 2 antibody.Observed band size:77kDa.

Immunohistochemistry analysis of paraffin-embedded Human tonsil using PKC beta 2 antibody.High-pressure and temperature Sodium Citrate pH 6.0 was used for antigen retrieval.
          Publications