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CXCR3 (DM208) Rabbit mAb

Anti-CXCR3 (DM208) Rabbit Monoclonal Antibody
5/5

$445.00

Cat.#:  28551

   Size:   100 μg

In Stock

          Product Description          
Cat.#:   28551
Product Name:   Anti-CXCR3(DM208) Rabbit Monoclonal Antibody
Synonyms:   CD182; CD183; CKR-L2; CMKAR3; GPR9; IP10-R; Mig-R; MigR
Description:    Anti-CXCR3 antibody(DM208) Rabbit Monoclonal Antibody
Background:    This gene encodes a G protein-coupled receptor with selectivity for three chemokines; termed CXCL9:Mig (monokine induced by interferon-g); CXCL10:IP10 (interferon-g-inducible 10 kDa protein) and CXCL11:I-TAC (interferon-inducible T cell a-chemoattractant). Binding of chemokines to this protein induces cellular responses that are involved in leukocyte traffic; most notably integrin activation; cytoskeletal changes and chemotactic migration. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. One of the isoforms (CXCR3-B) shows high affinity binding to chemokine; CXCL4:PF4 (PMID:12782716). [provided by RefSeq; Jun 2011]
Applications:    ELISA; Flow Cyt
Recommended Dilutions:    ELISA 1:5000-10000; Flow Cyt 1:100
Host Species:    Rabbit
Isotype:    Rabbit IgG
Purification:    Purified from cell culture supernatant by affinity chromatography
Species Reactivity:    Human CXCR3
Constituents:    Lyophilized from sterile PBS, pH 7.4. 5 % – 8% trehalose is added as protectants before lyophilization.
Storage & Shipping:    Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing).

Figure 1. Flow cytometry analysis with Anti-CXCR3 (DM208) on Expi293 cells transfected with human CXCR3 (Blue histogram) or Expi293 transfected with irrelevant protein (Red histogram).
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