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IDH1 Rabbit mAb

Anti-IDH1 Rabbit Monoclonal Antibody
5/5

$349.00

Cat.#:  N261565

   Size:   100 μl

In Stock

          Product Description          
Cat.#:   N261565
Product Name:   Anti-IDH1 Rabbit Monoclonal Antibody
Synonyms:   IDH1; PICD; Isocitrate dehydrogenase [NADP] cytoplasmic; IDH; Cytosolic NADP-isocitrate dehydrogenase; IDP; NADP(+)-specific ICDH; Oxalosuccinate decarboxylase
UNIPROT ID:   O75874
Background:    Genetic variations are associated with cartilaginous tumors such as enchondroma or chondrosarcoma. Mutations of Arg-132 to Cys, Gly or His abolish the conversion of isocitrate to alpha-ketoglutarate. Instead, alpha-ketoglutarate is converted to R(-)-2-hydroxyglutarate.
Immunogen:    A synthetic peptide of human Isocitrate dehydrogenase
Applications:    WB,IHC-P,IP
Recommended Dilutions:    WB: 1/500-1/1000 IHC: 1/50-1/100 IP: 1/20
Host Species:    Rabbit
Clonality:    Rabbit Monoclonal
Clone ID:    R05-2G5
MW:    Calculated MW: 47 kDa; Observed MW: 47 kDa
Isotype:    IgG
Purification:    Affinity Purified
Species Reactivity:    Human,Mouse,Rat
Conjugation:    Unconjugated
Modification:    Unmodified
Constituents:    PBS (without Mg2+ and Ca2+), pH 7.3 containing 50% glycerol, 0.5% BSA and 0.02% sodium azide
Research Areas:    Signal Transduction
Storage & Shipping:    Store at -20°C. Avoid repeated freezing and thawing

Immunohistochemistry analysis of paraffin-embedded Human Cholangiocarcinoma using Isocitrate dehydrogenase antibody.High-pressure and temperature Sodium Citrate pH 6.0 was used for antigen retrieval.

Western blot analysis of IDH1 in rat Brain, C6, 3T3, Hela lysates using IDH1 antibody.
          Publications