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Thrombomodulin Rabbit mAb

Anti-Thrombomodulin Rabbit Monoclonal Antibody
5/5

$349.00

Cat.#:  N261571

   Size:   100 μl

In Stock

          Product Description          
Cat.#:   N261571
Product Name:   Anti-Thrombomodulin Rabbit Monoclonal Antibody
Synonyms:   CD141; Fetomodulin; THBD; THRM; thrombomodulin; TM
UNIPROT ID:   P07204
Background:    Thrombomodulin (TM), also called CD141, is a type I membrane receptor that is specific to endothelial cells. TM has a cysteine-rich extracellular domain with six EGF-like regions. It forms a complex with Thrombin, which activates Protein C to generate activated Protein C (APC), an anticoagulant enzyme. APC together with Protein S inhibits coagulation by inactivating Factors Va and VIIIa. Deletion of the TM gene results in embryonic lethality in mice.
Immunogen:    A synthetic peptide of human Thrombomodulin
Applications:    WB,ICC/IF,IP
Recommended Dilutions:    WB: 1/500-1/1000 IF: 1/50-1/200 IP: 1/20
Host Species:    Rabbit
Clonality:    Rabbit Monoclonal
Clone ID:    R08-4C6
MW:    Calculated MW: 60 kDa; Observed MW: 95 kDa
Isotype:    IgG
Purification:    Affinity Purified
Species Reactivity:    Human
Conjugation:    Unconjugated
Modification:    Unmodified
Constituents:    PBS (without Mg2+ and Ca2+), pH 7.3 containing 50% glycerol, 0.5% BSA and 0.02% sodium azide
Research Areas:    Cardiovascular
Storage & Shipping:    Store at -20°C. Avoid repeated freezing and thawing

Western blot analysis of Thrombomodulin in Jurkat lysates using Thrombomodulin antibody.

Immunocytochemistry analysis of Thrombomodulin (green) in A549 using Thrombomodulin antibody,and DAPI(blue).
          Publications