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PKR Rabbit mAb

Anti-PKR Rabbit Monoclonal Antibody
5/5

$349.00

Cat.#:  N261608

   Size:   100 μl

In Stock

          Product Description          
Cat.#:   N261608
Product Name:   Anti-PKR Rabbit Monoclonal Antibody
Synonyms:   EIF2AK2; PKR; PRKR; Interferon-induced; double-stranded RNA-activated protein kinase; Eukaryotic translation initiation factor 2-alpha kinase 2; eIF-2A protein kinase 2; Interferon-inducible RNA-dependent protein kinase; P1/eIF-2A protein k
UNIPROT ID:   P19525
Background:    PKR a protein kinase of the PEK family. Upon binding double-stranded RNA, it becomes autophosphorylated and activated. Phosphorylates and inhibits the alpha subunit of eIF2 alpha, which leads to an inhibition of the initiation of protein synthesis.
Immunogen:    A synthetic peptide of human PKR
Applications:    WB,IHC-F,IHC-P,ICC/IF,IP
Recommended Dilutions:    WB: 1/500-1/1000 IHC: 1/50-1/100 IF: 1/50-1/200 IP: 1/20
Host Species:    Rabbit
Clonality:    Rabbit Monoclonal
Clone ID:    R08-2C8
MW:    Calculated MW: 62 kDa; Observed MW: 74 kDa
Isotype:    IgG
Purification:    Affinity Purified
Species Reactivity:    Human
Conjugation:    Unconjugated
Modification:    Unmodified
Constituents:    PBS (without Mg2+ and Ca2+), pH 7.3 containing 50% glycerol, 0.5% BSA and 0.02% sodium azide
Research Areas:    Signal Transduction
Storage & Shipping:    Store at -20°C. Avoid repeated freezing and thawing

Immunocytochemistry analysis of PKR(green) in Hela using PKR antibody,and DAPI(blue)

Western blot analysis of PKR in K562, Hela lysates using PKR antibody.

Immunohistochemistry analysis of paraffin-embedded Human Cholangiocarcinoma using PKR antibody. High-pressure and temperature Sodium Citrate pH 6.0 was used for antigen retrieval.
          Publications